Over 60 Years of Medical Expertise

The skin care experts at E45 are
committed to creating the best skin
care products for everyone, at every
age, every day of the year.

Helping people to realise their best skin

The skin care experts at E45 know
your skin. Realise your best skin
and improve skin health with E45.

E45 with you in mind

We are there for your skin: to
protect, maintain and improve skin
health. Feel confident and at ease
in your own skin with the E45 range
of good skin care products.

Perfect for everyone, regardless of skin type

Take your first step towards great
skin with our E45 good skin care
products and advice, developed by
skin care experts.


Over 60 Years of
Medical Expertise:

Created with you in mind


In 1952 we released our first product—E45 cream. It was created by a Boots chemist in response to a customer request for a product that would soothe the skin in addition to having protective qualities.

In 1963 physicians noticed E45 cream was a beneficial treatment for dry skin conditions. At this time we only promoted our products to hospital sales departments. It wasn’t until 1980 that E45 cream was introduced to the pharmacy and retail establishments, where it was recognised for its dry skin expertise.

In the 1990's we extended our product range to include a complete emollient therapy line.  The feedback was so positive that we continued to create products with our customers in mind. We strive to continue to serve our customers needs and produce the very best for all skincare regime needs.

New E45 Fast Acting Spray Moisturiser

New E45 Fast Acting Spray Moisturiser

The intense protection of E45 now in a fast absorbing spray

Treating eczema can be easy as 1,2,3.

Treating eczema can be easy as 1,2,3.

4/5 mums* have already seen the difference in using a 3 step programme supported by the National Eczema Society.**

E45 Product Range

E45 Product Range

Learn more about our leading moisturisers for dry skin.

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